The Osmosis Unit

26 Cotlands Park, Longniddry East Lothian Scotland EH32 0QX

44 (0)1875 852761                 

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Pulse Reverse Osmosis
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Publications presently in press from The Osmosis Unit

The following are research papers produced by The Osmosis Unit and presently in press.

bulletKindlenís Physiology, Churchill Livingston, 2003 Chapter 14 Fluid and electrolytes, Chapter 14

This chapter gives the background to fluid and electrolyte therapy and how this relates to Pulse Reverse Osmosis. This book is scheduled for general release in September 2003.

bulletChanges in pulse rate, plasma osmotic pressure and blood pressure during simulated dives. Prior FGR, Pimlott J Stuchbury V, and Bryson P,   Submitted to ASEM 2003

This paper describes the first of a number of diving experiments where we measured colloid osmotic pressure changes during diving. This may give a better insight into the development of the bends

bulletAlcoholic fixation of blood to surgical instruments- a possible factor in the surgical transmission of CJD? Prior FGR, Fernie K, Renfrew A, Heneaghan G. Submitted to Journal of Hospital Infection 2003

The Osmosis Unit has been working with Trust Sterile Services, a surgical instrument cleaning company to develop a protein cleaning test. As part of this research consultancy the observation that alcohol glues blood onto surgical instruments was noted.  This paper highlights the significance of this on surgical transmission of CJD.  


Publications on PRO

bulletThe following is a bibliography of research papers published on PRO to date.


  1. Prior FGR, Pressure Pulse and Perfusion, Developing a new theory of blood pressure, J Vasc Res, Abstracts 22nd meeting of the European Society for Microcirculation, 2002, 39(S1), p37
  2. Prior FGR, Pimlott J and Bryson P, Diving , pulse and blood pressure, Diving Diseases Research Centre Newsletter, July 2001.
  3. Prior FGR, Plasma Colloid Osmotic Pressure in the Critically Ill, Care of the Critically Ill, 1999;15: 167-172
  4. Prior FGR, Morecroft V, Ferguson R, Gourlay T, Taylor KM Oedema, Starling and Pulse Reverse Osmosis: towards a possible biochemical marker for oedema. Int J Art Orgs 1999; 22 : 138-144
  5. Hope SA, Prior FGR, Z Slavik, Change in COP in children following cardiac bypass surgery Int J Intensive care 1998; 24(S1); S 177
  6. Prior FGR, Effect of change in pore size on the COP of plasma expanders, Int J Intensive Care 1998: 24(S1): S146
  7. Prior FGR, Understanding Osmosis, A Pharmaceutical Guide, Advanced Instruments, Norwood, Massachusetts 1998
  8. Prior FGR Investigation of the osmotic and hydrostatic pressures involved in pulse reverse osmosis. PhD thesis, University of Wales, 1998
  9. Prior FGR, Morecroft V, Gourlay T, Taylor KM. The Therapeutic Significance of Pulse Reverse Osmosis. Int J Artif Orgs., 1996; 19(8), 487-492
  10. Prior FGR, Morecroft T, Gourlay T and Taylor KM. Further testing of Pulse Reverse Osmosis, A new theory of the maintenance and control of blood pressure. Int J Artificial Organs 1995;18; 469
  11. Prior FGR, Morecroft T, Gourlay T and Taylor KM. Further testing of Pulse Reverse Osmosis, A new theory of the maintenance and control of blood pressure. Int J Artificial Organs 1995;18; 469
  12. Prior FGR, Gourlay T, Taylor KM. Pulse Reverse Osmosis: a new theory in the maintenance of fluid balance. Perfusion 1995; 10: 159-170
  13. Prior FGR, Gourlay T, Taylor KM. The development and testing of a new theory of fluid exchange Int J Artificial Organs/1994 vol 17 no 8 p429
  14. Prior FGR, Hormonal response to fluid administration in cardiac surgery patients, Perfusion 1994; 9: 2 88-292
  15. Book Review, Allegra C, Intagliatta M., Messmer K eds 1993, Progress in applied microcirculation. Vol 20: Vasomotion and Flowmotion viii in Perfusion 1994;9:149
  16. Prior FGRPulsing reverse osmosis: A new mechanism for fluid exchange. Proceedings of the society of perfusionists of Great Britain and Northern Ireland, Abstract 2 1991
  17. Prior FGR, Pulsing Reverse Osmosis as the mechanism underlying fluid exchange, Medical Hypotheses, 1991; 36: p 109-113


For further information click one of these links

Pulse reverse osmosis

Colloid Osmotic pressure


Scientific Consultancy




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Last modified: 07/05/06